01 Research Summary
Our laboratory conducts research on human sleep and sleepiness in the fields of behavioral science, psychophysiology, and neuroscience. Currently, our main research topics are: (1) a method for the continuous estimation of response speed through non-contact measurement of eyelid indicators, and (2) the estimation of dream emotions during REM sleep using electroencephalography (EEG).
(1) A Method for the Continuous Estimation of Response Speed Through Non-contact Measurement of Eyelid Indices
The Psychomotor Vigilance Test (PVT) is highly sensitive to sleep manipulations (e.g., sleep deprivation, sleep restriction) and has been used as the gold standard for assessing performance deficits associated with drowsiness. However, one limitation of the PVT is that it cannot be performed simultaneously with other tasks. To address this, we have successfully developed a technique that enables high-accuracy, continuous estimation of response speed—the key PVT performance metric—for unknown populations using only eyelid-based indices measured by non-contact eye trackers or webcams. This technology is expected to be effective even in situations and for populations where drowsiness detection has been difficult with conventional methods. By applying this technology, we aim to establish a technique for detecting driver drowsiness, thereby preventing accidents. Furthermore, we aim to establish a simple method for assessing vigilance for various groups, including students, e-sports players, and office workers. Through this technology, we will advance research toward understanding and preventing drowsiness, with the goal of realizing a safe and productive society.
(2) Estimation of Dream Emotions During REM Sleep Using Electroencephalography (EEG)
We are developing a technology to accurately estimate dream emotions during REM sleep using EEG, aiming to establish a "No-report paradigm for dream emotion" that allows for the objective evaluation of dream emotions without relying on subjective reports. By establishing this technology, we aim to elucidate the function of dream emotions. Additionally, we are working on the development of techniques to reduce unpleasant dream emotions. By integrating these techniques, we aim to develop a closed-loop nightmare reduction technology.
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02 Major achievements
Yoko Suzuki+, Chihiro Suzuki+, Yurina Suzuki, Fusae Kawana, Tomohiro Ohigashi, Kazushi Maruo, Takahiro Watanabe, Takashi Abe (+Co-first authors) (2025). Effects of Optimal Timed Automatic Awakening from a Short Daytime Nap on Cognitive Performance, Alertness, and Fatigue. Scientific Reports.
Luis Alfredo Moctezuma, Marta Molinas, Takashi Abe. (2025). From high- to low-density EEG for automatic classification of dream experiences during stage 2 of NREM. SLEEP Advances, zpaf066.
https://doi.org/10.1093/sleepadvances/zpaf066Kazuki Sato, Satomi Okabe, Yoko Suzuki, Takashi Abe. (2025). Targeted memory reactivation during REM sleep may selectively enhance the late positive potential amplitude in previously encountered negative images: Preliminary findings. SLEEP Advances, 6(2), zpaf034.
https://doi.org/10.1093/sleepadvances/zpaf034Luis Alfredo Moctezuma, Marta Molinas, Takashi Abe. (2025). Unlocking Dreams and Dreamless Sleep: Machine Learning Classification with Optimal EEG Channels. BioMed Research International, 2025, 3585125.
https://doi.org/10.1155/bmri/3585125Zhiwei Fan†, Yunyao Zhu†, Chihiro Suzuki, Yoko Suzuki, Yumi Watanabe, Takahiro Watanabe, Takashi Abe (+Co-first authors) (2024). Binaural beats at 0.25 Hz shorten the latency to slow-wave sleep during daytime naps. Scientific Reports, 14, 26062.
https://doi.org/10.1038/s41598-024-76059-9Takashi Abe (2023). PERCLOS-based technologies for detecting drowsiness: current evidence and future directions, SLEEP Advances, 4(1), zpad006.
https://doi.org/10.1093/sleepadvances/zpad00603 Education/Academic background and major awards
Education/Academic background
| 2000-2008 | Research fellow, Japan Society for the Promotion of Science (Hiroshima University) |
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| 2008 | Ph.D.Graduate School of Biosphere Science, Hiroshima University |
| 2008-2010 | Postdoctoral fellow, Japan Somnology Center, Neuropsychiatric Research Institute, Tokyo, Japan |
| 2010-2013 | Research fellow, Japan Somnology Center, Neuropsychiatric Research Institute |
| 2011-2013 | Postdoctoral fellow for Research Abroad, Japan Society for the Promotion of Science (Pennsylvania University School of Medicine) |
| 2013-2016 | Aerospace project research associate, Japan Aerospace Exploration Agency |
| 2016-2017 | Senior researcher, National Institute of Advanced Industrial Science and Technology |
| 2017-2025 | Associate professor, International Institute for Integrative Sleep Medicine(WPI-IIIS), University of Tsukuba |
| 2025-Present | Specially Appointed Associate professor, International Institute for Integrative Sleep Medicine(WPI-IIIS), University of Tsukuba |
Awards
| Zhiwei Fan (2025) | The 30th Japanese Society of Sleep Research, Young Investigator Award |
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| Takahiro Noguchi (2024) | Excellent Poster Award, 2024 Frontier Meeting (Autumn), Japan Society of Physiological Anthropology |
| Ayuka Hirayama (2024) | Excellent Poster Award, 2024 Frontier Meeting (Autumn), Japan Society of Physiological Anthropology |
| Luis Alfredo Moctezuma (2024) | Best Poster Presentation Award, Asian Society of Sleep Medicine Interim Meeting 2024 |
| Ayuka Hirayama (2024) | Best Research Presentation Award, The 33rd Annual Meeting of the Japanese Society of Sleep and Environment |
| Takashi Abe (2023) | Best Presentation Award, The 45th Annual Meeting of the Japanese Society of Sleep Research |
| Satomi Okabe (2023) | Excellent Presentation Award, The 84th Annual Meeting of the Japan Society of Physiological Anthropology |
| Satomi Okabe (2022) | Excellent Presentation Award, The 56th Annual Meeting of the Japanese Association for the Study of Taste and Smell |
| Yoko Suzuki (2022) | The 27th Japanese Society of Sleep Research Young Investigator Award |
Core Group
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Neuroscience
Masashi Yanagisawa
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Neuroscience
Takeshi Sakurai
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Neuroscience
Hiromasa Funato
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Neuroscience
Yu Hayashi
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Neuroscience
Michael Lazarus
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Neuroscience
Yo Oishi
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Neuroscience
Masanori Sakaguchi
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Neuroscience
Kaspar Vogt
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Neuroscience
Katsuyasu Sakurai
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Neuroscience
Sakiko Honjoh
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Neuroscience
Hirofumi Toda
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Neuroscience
Arisa Hirano
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Neuroscience
Robert Greene
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Neuroscience
Qinghua Liu
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Drug discovery
Noriki Kutsumura
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Drug discovery
Tsuyoshi Saitoh
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Human sleep
Tomohiro Okura
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Human sleep
Takashi Kanbayashi
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Human sleep
Takashi Abe
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behavioral science
Shun Nakajima
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Data Science
Hiroyuki Kitagawa
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Data Science
Shoi Shi
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Data Science
Masao Iwagami







