01 Research Summary
Our laboratory studies human sleep and sleepiness in the fields of behavioral science, psychophysiology, and neuroscience. Currently, we are conducting research on three main topics: (1) understanding sleepiness, (2) understanding the psychological functions of sleep, and (3) developing novel methods for measuring sleep and wakefulness. (1) Understanding sleepiness: It is well known that sleep loss causes fluctuations in response times. This phenomenon is called “state instability.” However, the neural and physiological basis of state instability is not yet fully understood. We are conducting studies to elucidate the characteristics of state instability and the neural and physiological basis of this phenomenon. In addition, we are also investigating the factors that determine “sleepiness” that cannot be explained by conventional sleep-wake models. (2) Understanding the psychological functions of sleep: This research is being conducted in order to understand the psychological functions of human sleep. In particular, we are investigating the psychological effects of sleep intervention by administering stimuli during sleep. (3) Developing novel methods for measuring sleep and wakefulness: Currently, sleep and wakefulness are measured with electroencephalography and performance tests. We are developing objective and unobtrusive methods to more easily measure sleep and wakefulness.
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02 Major achievements
Abe, T., Ogawa, K., Nittono, H., & Hori, T. Neural generators of brain potentials before rapid eye movements during human REM sleep: A study using sLORETA. Clinical Neurophysiology, 119, 2044-2053. 2008.
Abe, T., Nonomura, T., Komada, Y., Asaoka, S., Sasai, T., Ueno, A., Inoue, Y. Detecting deteriorated vigilance using percentage of eyelid closure time during behavioral maintenance of wakefulness tests. International Journal of Psychophysiology. 82, 269-274. 2011.
Goel,N.,* Abe,T.,* Braun, M.E., Dinges,D.F. Cognitive Workload and Sleep Restriction Interact to Influence Sleep Homeostatic Responses. SLEEP. 37(11),1745-1756. 2014. (*Co-first authors)
03 Education/Academic background and major awards
Education/Academic background
200-2008 | Research fellow, Japan Society for the Promotion of Science (Hiroshima University) |
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2008-2010 | Postdoctoral fellow, Japan Somnology Center, Neuropsychiatric Research Institute, Tokyo, Japan |
2010-2013 | Research fellow, Japan Somnology Center, Neuropsychiatric Research Institute |
2011-2013 | Postdoctoral fellow for Research Abroad, Japan Society for the Promotion of Science (Pennsylvania University School of Medicine) |
2013-2016 | Aerospace project research associate, Japan Aerospace Exploration Agency |
2016-2017 | Senior researcher, National Institute of Advanced Industrial Science and Technology |
2017- | Associate professor, International Institute for Integrative Sleep Medicine(WPI-IIIS), University of Tsukuba |
Awards
2004 | Young Scientist Award Creative Research Award, The 15th World Congress of the International Society of Brain Electromagnetic Topography |
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2009 | The 14th Encouraging Prize of Japanese Society of Sleep Research |
2011 | Mitsui Sumitomo Insurance Welfare Foundation Award |
2012 | The 17th Encouraging Prize of Japanese Society of Sleep Research |
Core Group
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Neuroscience
Masashi Yanagisawa
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Neuroscience
Takeshi Sakurai
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Neuroscience
Hiromasa Funato
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Neuroscience
Yu Hayashi
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Neuroscience
Michael Lazarus
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Neuroscience
Yo Oishi
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Neuroscience
Masanori Sakaguchi
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Neuroscience
Kaspar Vogt
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Neuroscience
Katsuyasu Sakurai
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Neuroscience
Sakiko Honjoh
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Neuroscience
Hirofumi Toda
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Neuroscience
Arisa Hirano
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Neuroscience
Robert Greene
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Neuroscience
Qinghua Liu
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Drug discovery
Noriki Kutsumura
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Drug discovery
Tsuyoshi Saitoh
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Human sleep
Tomohiro Okura
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Human sleep
Takashi Kanbayashi
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Human sleep
Takashi Abe
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behavioral science
Shun Nakajima
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Data Science
Hiroyuki Kitagawa
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Data Science
Shoi Shi
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Data Science
Masao Iwagami