Takashi Abe

Affiliation:International Institute for Integrative Sleep Medicine, University of Tsukuba

Research Title

Human sleep

Understanding how sleep and sleepiness relate to the human mind and behavior

01 Research Summary

Our laboratory conducts research on human sleep and sleepiness in the fields of behavioral science, psychophysiology, and neuroscience. Currently, our main research topics are: (1) a method for the continuous estimation of response speed through non-contact measurement of eyelid indicators, and (2) the estimation of dream emotions during REM sleep using electroencephalography (EEG).

(1) A Method for the Continuous Estimation of Response Speed Through Non-contact Measurement of Eyelid Indices
The Psychomotor Vigilance Test (PVT) is highly sensitive to sleep manipulations (e.g., sleep deprivation, sleep restriction) and has been used as the gold standard for assessing performance deficits associated with drowsiness. However, one limitation of the PVT is that it cannot be performed simultaneously with other tasks. To address this, we have successfully developed a technique that enables high-accuracy, continuous estimation of response speed—the key PVT performance metric—for unknown populations using only eyelid-based indices measured by non-contact eye trackers or webcams. This technology is expected to be effective even in situations and for populations where drowsiness detection has been difficult with conventional methods. By applying this technology, we aim to establish a technique for detecting driver drowsiness, thereby preventing accidents. Furthermore, we aim to establish a simple method for assessing vigilance for various groups, including students, e-sports players, and office workers. Through this technology, we will advance research toward understanding and preventing drowsiness, with the goal of realizing a safe and productive society.

(2) Estimation of Dream Emotions During REM Sleep Using Electroencephalography (EEG)
We are developing a technology to accurately estimate dream emotions during REM sleep using EEG, aiming to establish a "No-report paradigm for dream emotion" that allows for the objective evaluation of dream emotions without relying on subjective reports. By establishing this technology, we aim to elucidate the function of dream emotions. Additionally, we are working on the development of techniques to reduce unpleasant dream emotions. By integrating these techniques, we aim to develop a closed-loop nightmare reduction technology.

Link

02 Major achievements

Yoko Suzuki+, Chihiro Suzuki+, Yurina Suzuki, Fusae Kawana, Tomohiro Ohigashi, Kazushi Maruo, Takahiro Watanabe, Takashi Abe (+Co-first authors) (2025). Effects of Optimal Timed Automatic Awakening from a Short Daytime Nap on Cognitive Performance, Alertness, and Fatigue. Scientific Reports.

Luis Alfredo Moctezuma, Marta Molinas, Takashi Abe. (2025). From high- to low-density EEG for automatic classification of dream experiences during stage 2 of NREM. SLEEP Advances, zpaf066.

https://doi.org/10.1093/sleepadvances/zpaf066

Kazuki Sato, Satomi Okabe, Yoko Suzuki, Takashi Abe. (2025). Targeted memory reactivation during REM sleep may selectively enhance the late positive potential amplitude in previously encountered negative images: Preliminary findings. SLEEP Advances, 6(2), zpaf034.

https://doi.org/10.1093/sleepadvances/zpaf034

Luis Alfredo Moctezuma, Marta Molinas, Takashi Abe. (2025). Unlocking Dreams and Dreamless Sleep: Machine Learning Classification with Optimal EEG Channels. BioMed Research International, 2025, 3585125.

https://doi.org/10.1155/bmri/3585125

Zhiwei Fan†, Yunyao Zhu†, Chihiro Suzuki, Yoko Suzuki, Yumi Watanabe, Takahiro Watanabe, Takashi Abe (+Co-first authors) (2024). Binaural beats at 0.25 Hz shorten the latency to slow-wave sleep during daytime naps. Scientific Reports, 14, 26062.

https://doi.org/10.1038/s41598-024-76059-9

Takashi Abe (2023). PERCLOS-based technologies for detecting drowsiness: current evidence and future directions, SLEEP Advances, 4(1), zpad006.

https://doi.org/10.1093/sleepadvances/zpad006

03 Education/Academic background and major awards

Education/Academic background

2000-2008 Research fellow, Japan Society for the Promotion of Science (Hiroshima University)
2008 Ph.D.Graduate School of Biosphere Science, Hiroshima University
2008-2010 Postdoctoral fellow, Japan Somnology Center, Neuropsychiatric Research Institute, Tokyo, Japan
2010-2013 Research fellow, Japan Somnology Center, Neuropsychiatric Research Institute
2011-2013 Postdoctoral fellow for Research Abroad, Japan Society for the Promotion of Science (Pennsylvania University School of Medicine)
2013-2016 Aerospace project research associate, Japan Aerospace Exploration Agency
2016-2017 Senior researcher, National Institute of Advanced Industrial Science and Technology
2017-2025 Associate professor, International Institute for Integrative Sleep Medicine(WPI-IIIS), University of Tsukuba
2025-Present Specially Appointed Associate professor, International Institute for Integrative Sleep Medicine(WPI-IIIS), University of Tsukuba

Awards

Zhiwei Fan (2025) The 30th Japanese Society of Sleep Research, Young Investigator Award
Takahiro Noguchi (2024) Excellent Poster Award, 2024 Frontier Meeting (Autumn), Japan Society of Physiological Anthropology
Ayuka Hirayama (2024) Excellent Poster Award, 2024 Frontier Meeting (Autumn), Japan Society of Physiological Anthropology
Luis Alfredo Moctezuma (2024) Best Poster Presentation Award, Asian Society of Sleep Medicine Interim Meeting 2024
Ayuka Hirayama (2024) Best Research Presentation Award, The 33rd Annual Meeting of the Japanese Society of Sleep and Environment
Takashi Abe (2023) Best Presentation Award, The 45th Annual Meeting of the Japanese Society of Sleep Research
Satomi Okabe (2023) Excellent Presentation Award, The 84th Annual Meeting of the Japan Society of Physiological Anthropology
Satomi Okabe (2022) Excellent Presentation Award, The 56th Annual Meeting of the Japanese Association for the Study of Taste and Smell
Yoko Suzuki (2022) The 27th Japanese Society of Sleep Research Young Investigator Award