Solving the mystery of sleep

Premier institute aiming to elucidate mechanisms of sleep/wake regulation
and the function of the sleep by conducting basic to translational research

Never Enough Sleep? Mouse Mutation Shown to Increase Daily Amounts and Need for Sleep (Published in PNAS)

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The 23rd Keio Medical Science Prize to be awarded to professor Masashi Yanagisawa

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Reversible Changes to Neural Proteins May Explain Sleep Need (published on Nature)

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Which neuronal pathways regulates sleep/wakefulness states? – Functional and structural interactions between neurons in hypothalamus and in brain stem – (Published on the Journal of Neuroscience)

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TOPICS

Director’s Message

We aim to solve one of the biggest black boxes of today’s neuroscience

Director Masashi Yanagisawa

Our discovery of the neuropeptide orexin and its prominent role in sleep/wake regulation has generated a highly active research fields in neurobiology of sleep and metabolism. However, the fundamental governing principle for the regulation of sleep pressure, e.g., (1)the question of what the neural substrate for “sleepiness” is, (2) We have to sleepy remains a mystery. We focus on sleep neurobiology, and aim to solve one of the biggest mysteries in today’s neuroscience.

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[consultation(sleepy mouse)]Q&A:about sleep

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1

Why do we dream?

A

1

The function of dreaming is still not well underst...

Q

2

Are there short sleepers?

A

2

Short sleepers are quite rare, much rarer than peo...

Q

3

What is narcolepsy?

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3

Narcolepsy is also known as the “dozing-off diseas...

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4

What sort of social majors have been taken for sleep improvement?

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As an example, Professor Mitsuo Hayashi of Hiroshi...

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IIIS Blog

2018.10.9

異国の地で目指すもの IIIS研究員・朴寅成さんインタビュー

2017年6月、国際統合睡眠医科学研究機構(IIIS)の佐藤・徳山・阿部研究室の一員として睡眠とエネルギー代謝に関する論文を発表した朴寅成(パク・インソン)さん。韓国・ソウルから日本の筑波大学へ進学...

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筑波大学 国際統合睡眠医科学研究機構

INTERNATIONAL

INSTITUTE FOR

INTERGRATIVE

SLEEP MEDICINE