About IIIS

We spend nearly one-third of our lives asleep. The mechanism and function of sleep, however, remains unclear. Many factors such as mental illnesses, food, drugs, and emotions, can affect sleep/wake regulation. Disorder of sleep is not only by itself a major problem in modern society, but also an established risk factor for metabolic syndrome and other lifestyle diseases.
Deficiencies in healthy sleep cause significant social losses, and are linked to traffic accidents due to excessive sleepiness, increased prevalence of mood disorders, increased suicide deaths, and an increased caregiving burden due to wandering and delirium in the elderly. Thus, while sleep has been a perpetual topic of scientific inquiry that keeps attracting many great minds, it is also an important field in which society demands the development of strategies to remedy sleep disorders and associated diseases.
We gather globally prominent scientists from multiple research fields contributing to the neurobiology of sleep. They cooperate together to elucidate the fundamental principles of sleep/wake regulation, and develop new strategies to assess and treat sleep diseases as well as the closely associated metabolic and mental disorders.



Feature of the lab

Our target field is Sleep biomedicine, which is an inherently interdisciplinary field in terms of methodology, spanning molecular genetics, cellular biology, neurophysiology, neurochemistry, pharmaceutical sciences, medicinal chemistry, and clinical and social medicine. While focusing on sleep, the field is also interdisciplinary with respect to its integral research targets, e.g., studying mood disorders as well as metabolic diseases that are closely associated with pathological variations in sleep/wake states.

Japan has been producing a number of researchers who have made significant accomplishments in the field of sleep biomedicine. Led by Director, prominent scientists from multiple research fields contributing to the neurobiology of sleep will come together. The mission of IIIS is to be a multidisciplinary, international hub for the research.
By creating a hierarchically flat organization similar to “departments” in the U.S. academia, all scientists in the department freely discuss science with each other regardless of their age or career stage, constantly seeking for opportunities for formal and informal cooperation.



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